Note! This page contains a snapshot of the exRNA Atlas for the "ExRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present Across Human Biofluids" paper published in Cell (Murillo et al., 2019). The latest release of the Atlas can always be found at https://exrna-atlas.org.
Each cell in this grid indicates the total number of biosamples collected and profiled for exRNAs from a biofluid-assay type combination.
Click the number in a given cell to view key metadata about the relevant biosamples:
For RNA-seq profiles, download the processed core results archive. This archive will contain read counts from all three stages of exceRpt (endogenous, exogenous miRNA and rRNA, and exogenous genomes). For qPCR profiles, download the qPCR targets file associated with this biosample. The file will contain different miRNA targets and associated Ct values for those targets.
For RNA-seq profiles, download the full results (alignments) for the first two stages of exceRpt (endogenous alignment and exogenous miRNA and rRNA alignment).
For RNA-seq profiles, download the original FASTQ source file.
This data is unavailable because the associated biosample has been deposited in a controlled access archive like dbGaP (or will be soon). Click the icon under the External References column to view any available links to controlled access archive(s) that contain data for this biosample. You can then request access to this biosample through those external databases.
Download Advanced Results
For RNA-seq profiles, download the taxonomy tree (either exogenous ribosomal RNA or exogenous genomic reads) created by exceRpt.
For RNA-seq profiles, download the full results (alignments) for the third stage of exceRpt (exogenous genomic alignment).
This data is unavailable because the associated biosample has been deposited in a controlled access archive like dbGaP (or will be soon). Click the icon under the External References column to view any available links to controlled access archive(s) that contain data for this biosample. You can then request access to this biosample through those external databases.
Download Metadata
Download the Biosample metadata document.
Download the Experiment metadata document.
Download the Donor metadata document.
Download all three metadata documents (Biosample, Experiment, and Donor) as a single file.
RNA Profile
View a histogram of reads mapped to various libraries.
External References
View links to external databases like SRA, dbGaP, GEO, etc. if the data is available in a public domain archive or controlled access archive. Otherwise, view the data access policy if the data is currently protected via embargo.
View PubMed reference, if available.
Click the number in a given cell to view key metadata about the relevant biosamples:
- Quality control metrics are displayed for each sample. You can learn more about the QC metrics by visiting the ERC Consortium QC Standards page.
- You can download data files from one sample at a time or in bulk. Use the icons in the Download Data column to download data files associated with an individual sample. Use the "Download Data Files for Samples" button at the top of the grid to download files in bulk. You can find more information about the available files below as well as on our Batch Download of Atlas Files tutorial. You can also view the Understanding exceRpt RNA-seq Analysis Results tutorial to better understand the various RNA-seq data files and their contents.
- You can download metadata files from one sample at a time or in bulk. Use the icons in the Download Metadata column to download metadata files associated with an individual sample. Use the "Download Metadata Files for Samples" button at the top of the grid to download files in bulk. You can find more information about the available files below as well as on our Batch Download of Atlas Files tutorial.
- You can view information about the dataset associated with a given biosample by clicking its Related Dataset Accession ID (found on the right side of the grid).
- You can process selected samples through the Atlas analysis tools by selecting your samples and then clicking the "Analyze Selected Samples" button at the top of the grid. View the Running Analyses and Viewing Analysis Results Using the exRNA Atlas tutorial for more information.
Legend of icons, listed in the order in which they appear in the grid columns:
Download DataFor RNA-seq profiles, download the processed core results archive. This archive will contain read counts from all three stages of exceRpt (endogenous, exogenous miRNA and rRNA, and exogenous genomes). For qPCR profiles, download the qPCR targets file associated with this biosample. The file will contain different miRNA targets and associated Ct values for those targets.
For RNA-seq profiles, download the full results (alignments) for the first two stages of exceRpt (endogenous alignment and exogenous miRNA and rRNA alignment).
For RNA-seq profiles, download the original FASTQ source file.
This data is unavailable because the associated biosample has been deposited in a controlled access archive like dbGaP (or will be soon). Click the icon under the External References column to view any available links to controlled access archive(s) that contain data for this biosample. You can then request access to this biosample through those external databases.
Download Advanced Results
For RNA-seq profiles, download the taxonomy tree (either exogenous ribosomal RNA or exogenous genomic reads) created by exceRpt.
For RNA-seq profiles, download the full results (alignments) for the third stage of exceRpt (exogenous genomic alignment).
This data is unavailable because the associated biosample has been deposited in a controlled access archive like dbGaP (or will be soon). Click the icon under the External References column to view any available links to controlled access archive(s) that contain data for this biosample. You can then request access to this biosample through those external databases.
Download Metadata
Download the Biosample metadata document.
Download the Experiment metadata document.
Download the Donor metadata document.
Download all three metadata documents (Biosample, Experiment, and Donor) as a single file.
RNA Profile
View a histogram of reads mapped to various libraries.
External References
View links to external databases like SRA, dbGaP, GEO, etc. if the data is available in a public domain archive or controlled access archive. Otherwise, view the data access policy if the data is currently protected via embargo.
View PubMed reference, if available.