The exRNA Atlas is the data repository of the Extracellular RNA Communication Consortium (ERCC). The repository includes small RNA sequencing and qPCR-derived exRNA profiles from human and mouse biofluids. All RNA-seq datasets are processed using version 4 of the exceRpt small RNA-seq pipeline (Rozowsky et al., 2019) and ERCC-developed quality metrics are uniformly applied to these datasets. If you're interested in submitting your RNA-seq or qPCR data to the Atlas, view our Submission Guide.

Above, in the upper right corner of this panel, you can use the ncRNA search bar to search the exRNA Atlas data for specific ncRNAs of interest. If your browser window is smaller, you will need to click the "hamburger" options icon to reveal the ncRNA search bar.

We also have a dedicated JSON-LD API that can be used for programmatic access to Atlas data and metadata. More information can be found on our API Documentation page.

The exRNA Explorer Tool enables the exploration of exRNA profiles from the Atlas using a variety of methods, including dimensionality reduction approaches such as principal component analysis (PCA), variational autoencoders (VAE), and uniform manifold approximation and projection (UMAP). Interactive visualizations of the data - which include scatter plots, heatmaps, UpSet plots, and boxplots - can be labeled by metadata characteristics such as disease state or biofluid. Users can extend the functionality of the tool by submitting custom analyses or downloading reduced data for further analysis.