Bringing exRNA Data and Analysis Tools Together

The exRNA Atlas is the data repository of the Extracellular RNA Communication Consortium (ERCC). The repository includes small RNA sequencing and qPCR-derived exRNA profiles from human and mouse biofluids. All RNA-seq datasets are processed using version 4 of the exceRpt small RNA-seq pipeline (Rozowsky et al., 2019) and ERCC-developed quality metrics are uniformly applied to these datasets. If you're interested in submitting your RNA-seq or qPCR data to the Atlas, view our Submission Guide.

Above, in the upper right corner of this panel, you can use the ncRNA search bar to search the exRNA Atlas data for specific ncRNAs of interest. If your browser window is smaller, you will need to click the "hamburger" options icon to reveal the ncRNA search bar.

We also have a dedicated JSON-LD API that can be used for programmatic access to Atlas data and metadata. More information can be found on our API Documentation page.

× Attention: If you're interested in viewing the version of the Atlas used in the Cell paper "ExRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present Across Human Biofluids" (Murillo et al., 2019), please see the associated Atlas Snapshot.

The exRNA Explorer Tool enables the exploration of exRNA profiles from the Atlas using a variety of methods, including dimensionality reduction approaches such as principal component analysis (PCA), variational autoencoders (VAE), and uniform manifold approximation and projection (UMAP). Interactive visualizations of the data - which include scatter plots, heatmaps, UpSet plots, and boxplots - can be labeled by metadata characteristics such as disease state or biofluid. Users can extend the functionality of the tool by submitting custom analyses or downloading reduced data for further analysis.

Getting Started
Select exRNA Profiles: (0 selected)
Select, view and download Atlas data by clicking one or more slices from one or more charts. Then, click the Search icon in the floating menubar to apply filters and view the results (grid opens in a new tab). Click the SelectAll icon to select all slices from all charts (i.e., all exRNA profiles in the Atlas) or click the DeselectAll icon to clear selections. Please note that the size of each slice (representing a profile count) has been log-transformed.
Overview of Studies
PI Name Organization Study Title Samples Published? Other Databases
Atlas Statistics exRNA Atlas Wiki

* QC standards for saliva are under revision.


Samples Processed
<3 Months Ago 425
3 to <6 Months Ago 12
6 to <12 Months Ago 0
≥12 Months Ago 9,925
Total: 10,362
Reads (Billions) Processed
<3 Months Ago 2.62
3 to <6 Months Ago 0.19
6 to <12 Months Ago 0.00
≥12 Months Ago 64.50
Total: 67.31
Datasets Processed
<3 Months Ago 9
3 to <6 Months Ago 1
6 to <12 Months Ago 0
≥12 Months Ago 67
Total: 77
(New) Conditions Processed
<3 Months Ago 0
3 to <6 Months Ago 0
6 to <12 Months Ago 0
≥12 Months Ago 35
Total: 35
  • v4.26.0 Atlas released - 365 new exRNA profiles. (2023-08-01)
  • v4.25.0 Atlas released - 72 new exRNA profiles. (2023-06-18)
  • v4.24.1 Atlas released - JSON-LD API with Full Documentation URL fix. (2022-06-24)
  • v4.24.0 Atlas released - The exRNA Explorer Tool. (2022-04-30)
  • v4.23.0 Atlas released - 2233 new exRNA profiles. (2022-03-02)
  • More...